Amygdala function and 5-HTT gene variants in adolescent anxiety and major depressive disorder.

@article{Lau2009AmygdalaFA,
  title={Amygdala function and 5-HTT gene variants in adolescent anxiety and major depressive disorder.},
  author={Jennifer Y. F. Lau and David A. Goldman and Beata Buzas and Stephen J. Fromm and Amanda E. Guyer and Colin Hodgkinson and Christopher S. Monk and Eric E. Nelson and Pei-Hong Shen and Daniel S. Pine and Monique Ernst},
  journal={Biological psychiatry},
  year={2009},
  volume={65 4},
  pages={349-55}
}
BACKGROUND Associations between a functional polymorphism in the serotonin transporter gene and amygdala activation have been found in healthy, depressed, and anxious adults. This study explored these gene-brain associations in adolescents by examining predictive effects of serotonin transporter gene variants (S and L(G) allele carriers vs. L(A) allele homozygotes) and their interaction with diagnosis (healthy vs. patients) on amygdala responses to emotional faces. METHODS Functional magnetic… CONTINUE READING
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