Amygdala dopamine levels are markedly elevated after self- but not passive-administration of cocaine.

@article{Wilson1994AmygdalaDL,
  title={Amygdala dopamine levels are markedly elevated after self- but not passive-administration of cocaine.},
  author={Julie M. Wilson and Jos{\'e} N. Nobrega and William A. Corrigall and Kathleen M. Coen and Kathleen Shannak and Stephen J. Kish},
  journal={Brain research},
  year={1994},
  volume={668 1-2},
  pages={39-45}
}
The influence of cocaine on rat brain monoaminergic neurotransmitters (dopamine, serotonin, noradrenaline) and their metabolites, and on binding of [3H]WIN 35,428 and [3H]GBR 12,935 to the dopamine transporter was measured after 4 weeks of cocaine exposure. Cocaine (mean daily dose 9.25 +/- 0.48 mg/kg) was self-administered (responders) or passively received (yoked) during sessions which lasted for 1 h per day. As compared with the controls, mean dopamine and serotonin levels were significantly… CONTINUE READING

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