Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults.

@article{Urry2006AmygdalaAV,
  title={Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults.},
  author={Heather L. Urry and Carien M van Reekum and Tom Johnstone and Ned H. Kalin and Marchell E. Thurow and Hillary S. Schaefer and Cory A. Jackson and Corrina J. Frye and Lawrence L. Greischar and Andrew L. Alexander and Richard J. Davidson},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2006},
  volume={26 16},
  pages={
          4415-25
        }
}
Among younger adults, the ability to willfully regulate negative affect, enabling effective responses to stressful experiences, engages regions of prefrontal cortex (PFC) and the amygdala. Because regions of PFC and the amygdala are known to influence the hypothalamic-pituitary-adrenal axis, here we test whether PFC and amygdala responses during emotion regulation predict the diurnal pattern of salivary cortisol secretion. We also test whether PFC and amygdala regions are engaged during emotion… CONTINUE READING

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