Amygdala and hippocampal volumes in relatives of patients with bipolar disorder: a high-risk study.

@article{Hajek2009AmygdalaAH,
  title={Amygdala and hippocampal volumes in relatives of patients with bipolar disorder: a high-risk study.},
  author={Tomas Hajek and Eva Gunde and Claire M. Slaney and Lukas Propper and Glenda M. MacQueen and Anne Duffy and Martin Alda},
  journal={Canadian journal of psychiatry. Revue canadienne de psychiatrie},
  year={2009},
  volume={54 11},
  pages={726-33}
}
OBJECTIVE Bipolar disorders (BD) have a strong genetic underpinning, yet no biological vulnerability markers for BD have yet been identified. To test whether amygdala or hippocampal volumes represent an endophenotype for BD, we measured mesiotemporal volumes in young affected and unaffected relatives of patients with BD (high-risk design). METHOD High-risk participants (aged 15 to 30 years) were recruited from families multiply affected with BD. They included 20 affected and 26 unaffected… CONTINUE READING

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