Amygdala activity in obsessive-compulsive disorder with contamination fear: a study with oxygen-15 water positron emission tomography.

@article{Heuvel2004AmygdalaAI,
  title={Amygdala activity in obsessive-compulsive disorder with contamination fear: a study with oxygen-15 water positron emission tomography.},
  author={Odile A. van den Heuvel and Dick J. Veltman and Henk J. Groenewegen and Raymond J. Dolan and Danielle C. Cath and Ronald Boellaard and Catalina T Mesina and Anton J. L. M. van Balkom and Patricia van Oppen and Menno P Witter and Adriaan A. Lammertsma and Richard van Dyck},
  journal={Psychiatry research},
  year={2004},
  volume={132 3},
  pages={225-37}
}
Previous imaging studies of obsessive-compulsive symptom states have implicated frontal-striatal and limbic regions in the pathophysiology of obsessive-compulsive disorder (OCD). Functional imaging studies, however, have yielded inconsistent results, presumably due to methodological differences (patient inclusion criteria, stimulus paradigm, imaging technique, and absence of control groups). In the present study, randomized presentation of contamination-related and neutral visual stimuli was… CONTINUE READING