Amplitude reduction of the mismatch negativity in first-degree relatives of patients with schizophrenia.

@article{Jessen2001AmplitudeRO,
  title={Amplitude reduction of the mismatch negativity in first-degree relatives of patients with schizophrenia.},
  author={Frank Jessen and Thomas Fries and Cezary M Kucharski and Tsunehiko Nishimura and Klaus Hoenig and Wolfgang Maier and Peter Falkai and Reinhard Heun},
  journal={Neuroscience letters},
  year={2001},
  volume={309 3},
  pages={185-8}
}
First-degree relatives of schizophrenic patients display alterations in various cognitive domains and their electrophysiological counterparts similar to schizophrenic subjects. The mismatch negativity (MMN) is an event-related potential that reflects sensory memory in the pre-attentive stage of auditory processing. An amplitude reduction of the MMN has been reported in schizophrenia. The present study investigated the MMN in patients with schizophrenia, first-degree relatives and control… CONTINUE READING