Amplified electrochemiluminescence detection of nucleic acids by hairpin probe-based isothermal amplification.


Here, we present a straightforward method for isothermal amplified detection of nucleic acids. In this proof-of-concept study, a specific DNA sequence is amplified through hairpin probe-based isothermal strand-displacement polymerization reaction and then detected via a sensitive and commercially available ECL detection platform. Results show that the DNA… (More)
DOI: 10.1039/c2an35367a