Amplified Silencing

@article{Baulcombe2007AmplifiedS,
  title={Amplified Silencing},
  author={David C. Baulcombe},
  journal={Science},
  year={2007},
  volume={315},
  pages={199 - 200}
}
  • D. Baulcombe
  • Published 12 January 2007
  • Biology, Medicine
  • Science
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Analysis of endogenous small RNAs indicated that a fraction derive from a biosynthetic mechanism that is similar to that of secondary siRNAs formed during RNAi, suggesting that small antisense transcripts derived from cellular messenger RNAs by RdRP activity may have key roles in cellular regulation. Expand
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Systemic, posttranscriptional silencing of transgenes in Nicotiana benthamiana was initiated in localized regions of the plant by introduction of transgene-homologous DNA fragments, including thoseExpand