Amplification of perforant-path EPSPs in CA3 pyramidal cells by LVA calcium and sodium channels.

@article{Urban1998AmplificationOP,
  title={Amplification of perforant-path EPSPs in CA3 pyramidal cells by LVA calcium and sodium channels.},
  author={Nathaniel N. Urban and Darrell A. Henze and Germ{\'a}n Barrionuevo},
  journal={Journal of neurophysiology},
  year={1998},
  volume={80 3},
  pages={
          1558-61
        }
}
The perforant path forms a monosynaptic connection between the cells of layer II of the entorhinal cortex and the pyramidal cells in hippocampal area CA3. Although this projection is prominent anatomically, very little is known about the physiological properties of this input. The distal location of these synapses suggests that somatically recorded perforant-path excitatory postsynaptic potentials (EPSPs) may be influenced by the activation of voltage-dependent channels in CA3 cells. We… CONTINUE READING

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