Amplification of a DEAD box protein gene in retinoblastoma cell lines.

@article{Godbout1993AmplificationOA,
  title={Amplification of a DEAD box protein gene in retinoblastoma cell lines.},
  author={Roseline Godbout and Jeremy Squire},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1993},
  volume={90 16},
  pages={7578-82}
}
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Here, we report that the mRNA… CONTINUE READING

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