Amplification of Trial-to-Trial Response Variability by Neurons in Visual Cortex

  title={Amplification of Trial-to-Trial Response Variability by Neurons in Visual Cortex},
  author={Matteo Carandini},
  journal={PLoS Biology},
  pages={83 - 92}
The visual cortex responds to repeated presentations of the same stimulus with high variability. Because the firing mechanism is remarkably noiseless, the source of this variability is thought to lie in the membrane potential fluctuations that result from summated synaptic input. Here this hypothesis is tested through measurements of membrane potential during visual stimulation. Surprisingly, trial-to-trial variability of membrane potential is found to be low. The ratio of variance to mean is… CONTINUE READING
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