Amplification of BCR Protein Associated with Oncogenesis in Human Hepatocellular Carcinoma


The BCR gene is located on human chromosome 22.The normal cellular BCR gene encodes a 160,000-daltonphosphoprotein associated with a serine/threonine kinaseactivity. The BCR protein is involved in signal transduction. We investigated the expression ofthe BCR protein in hepatocellular carcinoma (HCC),surrounding noncancerous liver tissue, liver cirrhosis(LC… (More)
DOI: 10.1023/A:1018864414582


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