AmpliSAS and AmpliHLA: Web Server Tools for MHC Typing of Non-Model Species and Human Using NGS Data.

@article{Sebastin2018AmpliSASAA,
  title={AmpliSAS and AmpliHLA: Web Server Tools for MHC Typing of Non-Model Species and Human Using NGS Data.},
  author={Alvaro San Sebasti{\'a}n and Magdalena Migalska and Aleksandra Biedrzycka},
  journal={Methods in molecular biology},
  year={2018},
  volume={1802},
  pages={
          249-273
        }
}
AmpliSAS and AmpliHLA are web server tools for automatic genotyping of MHC genes from high-throughput sequencing data. AmpliSAS is designed specifically to analyze amplicon sequencing data from non-model species and it is able to perform de-novo genotyping without any previous knowledge of the reference alleles. AmpliHLA is a human-specific version, it performs HLA typing by comparing sequenced variants against human reference alleles from the IMGT/HLA database. Here we describe four genotyping… CONTINUE READING

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