Amphotericin B-induced nephrotoxicity: a review.

@article{Fanos2000AmphotericinBN,
  title={Amphotericin B-induced nephrotoxicity: a review.},
  author={Vassilios Fanos and Luigi Cataldi},
  journal={Journal of chemotherapy},
  year={2000},
  volume={12 6},
  pages={463-70}
}
Amphotericin B is the gold standard for antifungal treatment for the most severe mycoses. However, adverse effects are common, with nephrotoxicity being the most serious, occurring early in the course of treatment, and usually being reversible in most patients. Tubular damage is a well known problem associated with amphotericin B therapy but acute renal failure is the most serious complication. Recent studies have examined ways to ameliorate the well-known toxicities of amphotericin B. A new… CONTINUE READING

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