Amphotericin B concentrations in saliva after application of 2% amphotericin B in orabase®

Abstract

2% amphotericin B in orabase® was applied to the buccal mucous membranes of healthy volunteers. Amounts of 1 g and 0.5 g were used. The experiments were performed during the day time as well as during the sleeping hours at night. At several intervals after application saliva samples were collected and the amphotericin B concentrations were determined… (More)
DOI: 10.1007/BF01641085