Amphotericin B- and fluconazole-resistant Candida spp., Aspergillus fumigatus, and other newly emerging pathogenic fungi are susceptible to basic antifungal peptides.

@article{Helmerhorst1999AmphotericinBA,
  title={Amphotericin B- and fluconazole-resistant Candida spp., Aspergillus fumigatus, and other newly emerging pathogenic fungi are susceptible to basic antifungal peptides.},
  author={E J Helmerhorst and Ingrid M. Reijnders and Wim van't Hof and Ina M. Simoons-Smit and Enno C. I. Veerman and Arie V Van Nieuw Amerongen},
  journal={Antimicrobial agents and chemotherapy},
  year={1999},
  volume={43 3},
  pages={702-4}
}
The present study shows that a number of basic antifungal peptides, including human salivary histatin 5, a designed histatin analog designated dhvar4, and a peptide from frog skin, PGLa, are active against amphotericin B-resistant Candida albicans, Candida krusei, and Aspergillus fumigatus strains and against a fluconazole-resistant Candida glabrata isolate. 

Citations

Publications citing this paper.
Showing 1-10 of 39 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 23 references

Peptide antibiotics

  • K. C Hazen
  • Lancet
  • 1997

Similar Papers

Loading similar papers…