Amphiregulin activates human hepatic stellate cells and is upregulated in non alcoholic steatohepatitis

Abstract

Amphiregulin (AR) involvement in liver fibrogenesis and hepatic stellate cells (HSC) regulation is under study. Non-alcoholic fatty liver disease (NAFLD) and its more severe form non-alcoholic steatohepatitis (NASH) may progress to cirrhosis and hepatocellular cancer (HCC). Our aim was to investigate ex vivo the effect of AR on human primary HSC (hHSC) and… (More)
DOI: 10.1038/srep08812

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Cite this paper

@inproceedings{Mckee2015AmphiregulinAH, title={Amphiregulin activates human hepatic stellate cells and is upregulated in non alcoholic steatohepatitis}, author={Chad Mckee and Barbara Sigala and Junpei Soeda and Angelina Mouralidarane and Maelle L. Morgan and Gianluigi Mazzoccoli and Francesca Rappa and Francesco Cappello and Daniela Cabibi and Valerio Pazienza and Claire Selden and Tania A D Roskams and Manlio Vinciguerra and Jude A. Oben}, booktitle={Scientific reports}, year={2015} }