Amphiphilic and hydrophilic nature of sheep and human platelet phosphotyrosine phosphatase forms.

@article{HernndezHernndez1999AmphiphilicAH,
  title={Amphiphilic and hydrophilic nature of sheep and human platelet phosphotyrosine phosphatase forms.},
  author={{\'A}ngel Hern{\'a}ndez-Hern{\'a}ndez and Marcial Llanillo and M. C. Ceballos Rodr{\'i}guez and Francisco P G{\'o}mez and Jes{\'u}s S{\'a}nchez-Yag{\"u}e},
  journal={Biochimica et biophysica acta},
  year={1999},
  volume={1419 2},
  pages={195-206}
}
To date, although at least 75 different PTPases (protein-tyrosine-phosphate-phosphohydrolase, EC 3.1.3.48) have been identified, those detected in platelets are rather scarce. Based on previous results from our laboratory, we investigated the existence of new PTPases in platelets. Triton X-114 phase partitioning of Triton X-100-solubilized human and sheep platelet membranes allowed PTPase to be recovered in the detergent-rich (40-35%, respectively) and -poor phases (60-65%, respectively… CONTINUE READING