Amphipathic CRAC-Containing Peptides Derived from the Influenza Virus A M1 Protein Modulate Cholesterol-Dependent Activity of Cultured IC-21 Macrophages

@article{DuninaBarkovskaya2018AmphipathicCP,
  title={Amphipathic CRAC-Containing Peptides Derived from the Influenza Virus A M1 Protein Modulate Cholesterol-Dependent Activity of Cultured IC-21 Macrophages},
  author={Antonina Dunina-Barkovskaya and Kh. S. Vishnyakova and Andrei Golovko and Alexander Migranovich Arutyunyan and Ludmila A. Baratova and O. V. Bathishchev and Victor A Radyukhin},
  journal={Biochemistry (Moscow)},
  year={2018},
  volume={83},
  pages={982-991}
}
Entry of many viral and bacterial pathogens into host cells depends on cholesterol and/or cholesterol-enriched domains (lipid rafts) in the cell membrane. Earlier, we showed that influenza virus A matrix protein M1 contains amphipathic α-helices with exposed cholesterol-recognizing amino acid consensus (CRAC) motifs. In order to test possible functional activity of these motifs, we studied the effects of three synthetic peptides corresponding to the CRAC-containing α-helices of the viral M1… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 47 REFERENCES

Effects of cell culture density on phagocytosis parameters in IC 21 macrophages, Biochemistry (Moscow) Suppl

Vishniakova, S Kh., I. I. Kireev, Dunina Barkovskaya, A. Ya
  • Ser. A: Membrane Cell Biol.,
  • 2011
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Serum-induced inhibition of the phagocytic activity of cultured macrophages IC-21

  • Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology
  • 2009
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

An intrin  sically disordered peptide facilitates non  endosomal cell entry

G. Y. Di Veroli, C. Fornari, +5 authors D. I. Jodrell
  • Angew . Chem . Int .
  • 2016

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