Amphetamine-induced circling behaviour in MPTP-lesioned mice.

Abstract

This study was designed to examine the effect of intrastriatal administration of MPTP on (+)-amphetamine-induced circling behaviour in mice. The results demonstrate that (+)-amphetamine elicits circling behaviour in MPTP-lesioned animals. MPTP produced a 70% depletion of striatal dopamine concentration. 

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Cite this paper

@article{Fung1985AmphetamineinducedCB, title={Amphetamine-induced circling behaviour in MPTP-lesioned mice.}, author={Yu-Fai Fung and C E Troxel}, journal={The Journal of pharmacy and pharmacology}, year={1985}, volume={37 12}, pages={922-3} }