Amphetamine in rat brain after intraperitoneal injection of N-alkylated analogues

@article{Nazarali1983AmphetamineIR,
  title={Amphetamine in rat brain after intraperitoneal injection of N-alkylated analogues},
  author={Adil J. Nazarali and Glen B. Baker and Ronald Thomson Coutts and Franco M. Pasutto},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={1983},
  volume={7},
  pages={813-816}
}
13 Citations
Chapter 3 Amphetamines
Neuropsychopharmacology of the Trace Amines
TLDR
Comparisons with other data show that the anorectic action of S-phenylethylamine can be distinguished from its hypodipsic ef~ect, its rein~orcing e~~ect as determined in the conditioned place-pre~erence test, and its ability to induce behavioural stereotypy.
Prodrugs of Trace Amines
TLDR
In the laboratory, the usefulness of prodrugs are investigated with the hope that they may alter advantageously the pharmacokinetics of the amine released by the prodrug, such that brain levels of amine are increased, prolonged or better controlled.
Prodrugs of β-Phenylethylamine and Tryptamine: Studies in the Rat
TLDR
It has been demonstrated that administration of either of these amines to rodents produces marked behavioural effects and one of the most pronounced effects seen in the brains of laboratory animals after administration of most monoamine oxidase (MAO)-inhibiting antidepressants is a marked increase in concentrations of PE and T.
N-(3-chloropropyl)phenylethylamine as a possible prodrug of β-phenylethylamine: Studies in the rat brain
Trace Amines
TLDR
The TNMT based assay, in conjunction with in situ microdialysis, was used to examine the content of p-tym and PEA in the extracellular space of the rat hypothalamus and striatum and both amines were detected at levels similar to those observed for more accepted neurotransmitters such as the catecholamines and histamine.
ILLEGAL OR LEGITIMATE USE? PRECURSOR COMPOUNDS TO AMPHETAMINE AND METHAMPHETAMINE
TLDR
In this review, potential precursor compounds are described, including their medical use and major clinical effects and their metabolic profiles, as well as some clues which help to identify the sources.
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