Amperometric immunoassay for the obesity biomarker amylin using a screen printed carbon electrode functionalized with an electropolymerized carboxylated polypyrrole

  title={Amperometric immunoassay for the obesity biomarker amylin using a screen printed carbon electrode functionalized with an electropolymerized carboxylated polypyrrole},
  author={Gonzalo Mart{\'i}nez-Garc{\'i}a and Esther S{\'a}nchez-Tirado and Araceli Gonz{\'a}lez-Cort{\'e}s and Paloma Y{\'a}{\~n}ez‐Sede{\~n}o and Jos{\'e} Manuel Pingarr{\'o}n},
  journal={Microchimica Acta},
AbstractAmylin (the islet amyloid polypeptide) is a hormone related to adiposity, hunger and satiety. It is co-secreted with insulin from pancreatic B-cells. An amperometric immunosensor is presented here for the determination of amylin. It is making use of a screen printed carbon electrode (SPCE) functionalized with electropolymerized poly(pyrrole propionic acid) (pPPA) with abundant carboxyl groups that facilitate covalent binding of antibody against amylin. A competitive immunoassay was… 
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