Amperometric detection of stimulus-induced quantal release of catecholamines from cultured superior cervical ganglion neurons.

@article{Zhou1995AmperometricDO,
  title={Amperometric detection of stimulus-induced quantal release of catecholamines from cultured superior cervical ganglion neurons.},
  author={Zhaohui Zhou and Stanley Misler},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1995},
  volume={92 15},
  pages={6938-42}
}
Amperometry has been used for real-time electrochemical detection of the quantal release of catecholamines and indolamines from secretory granules in chromaffin and mast cells. Using improved-sensitivity carbon fiber electrodes, we now report the detection of quantal catecholamine release at the surface of somas of neonatal superior cervical ganglion neurons that are studded with axon varicosities containing synaptic vesicles. Local application of a bath solution containing high K+ or black… CONTINUE READING