Amoxapine as an antipsychotic: comparative study versus haloperidol.

  title={Amoxapine as an antipsychotic: comparative study versus haloperidol.},
  author={Imran Bashir Chaudhry and Nusrat Husain and Salahuddin J. Khan and Sareer Badshah and Bill Deakin and Shitij Kapur},
  journal={Journal of clinical psychopharmacology},
  volume={27 6},
It has been proposed that the lack of extrapyramidal side effects of atypical antipsychotic drugs is caused by their fast dissociation or low affinity for the D2 receptor or their concomitant high affinity for other receptors, for example, 5HT2 and D4. We noted that amoxapine, an established antidepressant, has affinity for 5HT2 and D2 receptors, and its… CONTINUE READING