Amorphisation of Nifluminic Acid with Polyvinylpyrrolidone Prepared Solid Dispersion to Reach Rapid Drug Release

This paper describes the enhancement of dissolution rate of nifluminic acid by spray dry process, as a solid dispersion method using polyvinylpyrrolidone (PVP C-15) as a water soluble polymer. Using solid dispersions as a well-known principle on an industrial scale, it has to be combined with low-cost and repetable manufacturing method. Therefore, the aim… (More)