Amorpha-4,11-diene synthase of Artemisia annua: cDNA isolation and bacterial expression of a terpene synthase involved in artemisinin biosynthesis.

Abstract

Artemisia annua, an indigenous plant to Korea, contains an antimalarial sesquiterpene, artemisinin. The first committed step of artemisinin biosynthesis is the cyclization of farnesyl diphosphate by a sesquiterpene synthase to produce an amorphane-type ring system. The aims of this research were to molecularly clone and express amorpha-4,11-diene synthase… (More)

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@article{Chang2000Amorpha411dieneSO, title={Amorpha-4,11-diene synthase of Artemisia annua: cDNA isolation and bacterial expression of a terpene synthase involved in artemisinin biosynthesis.}, author={Y. J. Chang and S. H. Song and S. H. Park and S. U. Kim}, journal={Archives of biochemistry and biophysics}, year={2000}, volume={383 2}, pages={178-84} }