Amodiaquine resistance is not related to rare findings of pfmdr1 gene amplifications in Kenya.

@article{Holmgren2006AmodiaquineRI,
  title={Amodiaquine resistance is not related to rare findings of pfmdr1 gene amplifications in Kenya.},
  author={Gabrielle Holmgren and Anders Bj{\"o}rkman and Jos{\'e} Pedro Gil},
  journal={Tropical medicine & international health : TM & IH},
  year={2006},
  volume={11 12},
  pages={1808-12}
}
OBJECTIVES Many countries are now adopting artemisinin-based combination therapy (ACT) for treatment of Plasmodium falciparum malaria. In multi-drug resistant areas in South East Asia amplifications of the pfmdr1 gene are frequent and tentatively associated with reduced susceptibility to the common quinoline partner drugs mefloquine and lumefantrine. In Africa where amodiaquine is one of the favoured quinoline partner drugs in ACT, studies on multi-drug resistance associated pfmdr1 gene… CONTINUE READING

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