Amniotic membrane maintains the phenotype of rabbit retinal pigment epithelial cells in culture.

@article{Stanzel2005AmnioticMM,
  title={Amniotic membrane maintains the phenotype of rabbit retinal pigment epithelial cells in culture.},
  author={Boris V. Stanzel and Edgar M. Espana and Martin Grueterich and Tetsuya Kawakita and Jean-marie Parel and Scheffer C. G. Tseng and Susanne Binder},
  journal={Experimental eye research},
  year={2005},
  volume={80 1},
  pages={103-12}
}
The success of surgical removal of choroidal neovascularisation followed by transplantation of autologous retinal pigment epithelial cells (RPE) for age-related macular degeneration (ARMD) may be limited by damage in Bruch's membrane. We investigated whether amniotic membrane (AM) might be used as an alternative basement membrane-containing matrix to support RPE growth and differentiation. Primary RPE plastic cultures were established from freshly enucleated Dutch belted rabbit eyes in DMEM/F12… CONTINUE READING
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