Amniotic fluid stem cells improve survival and enhance repair of damaged intestine in necrotising enterocolitis via a COX-2 dependent mechanism.

@article{Zani2014AmnioticFS,
  title={Amniotic fluid stem cells improve survival and enhance repair of damaged intestine in necrotising enterocolitis via a COX-2 dependent mechanism.},
  author={Augusto Zani and Mara Cananzi and Francesco Fascetti-Leon and Giuseppe Lauriti and Virpi V. Smith and Sveva Bollini and Marco Ghionzoli and Antonello D'Arrigo and Michela Pozzobon and Martina Piccoli and Amy Hicks and Jack Wells and Bernard Siow and Neil J Sebire and Colin Bishop and A. Almagro Le{\'o}n and Anthony A. Atala and Mark F. Lythgoe and Agostino Pierro and Simon Eaton and Paolo De Coppi},
  journal={Gut},
  year={2014},
  volume={63 2},
  pages={
          300-9
        }
}
OBJECTIVE Necrotising enterocolitis (NEC) remains one of the primary causes of morbidity and mortality in neonates and alternative strategies are needed. Stem cells have become a therapeutic option for other intestinal diseases, which share some features with NEC. We tested the hypothesis that amniotic fluid stem (AFS) cells exerted a beneficial effect in a neonatal rat model of NEC. DESIGN Rats intraperitoneally injected with AFS cells and their controls (bone marrow mesenchymal stem cells… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 60 CITATIONS, ESTIMATED 57% COVERAGE

Stem Cell Therapy in the Treatment of Inflammatory Bowel Disease Mini Review

  • 2014
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2013
2019

CITATION STATISTICS

  • 2 Highly Influenced Citations

  • Averaged 9 Citations per year from 2017 through 2019

References

Publications referenced by this paper.
SHOWING 1-10 OF 60 REFERENCES

Amniotic fluid inhibits Toll-like receptor 4 signaling in the fetal and neonatal intestinal epithelium.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2012

Human and murine amniotic fl uid c - Kit + Lincells display hematopoietic activity

A Ditadi, P deCoppi, O Picone
  • Blood
  • 2009