Amniocentesis and chorionic villus sampling for prenatal diagnosis.

  title={Amniocentesis and chorionic villus sampling for prenatal diagnosis.},
  author={Žarko Alfirevi{\'c} and Karin M Sundberg and Sara Brigham},
  journal={The Cochrane database of systematic reviews},
BACKGROUND A major disadvantage of second trimester amniocentesis is that the result is usually available only after 18 weeks' gestation. Chorionic villus sampling (CVS) and early amniocentesis can be done between 9 and 14 weeks and offer an earlier alternative. OBJECTIVES The objective was to assess comparative safety and accuracy of second trimester amniocentesis, early amniocentesis, transcervical and transabdominal CVS. SEARCH STRATEGY We searched the Cochrane Pregnancy and Childbirth… CONTINUE READING
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