Ammonium uptake and urea production in hepatocytes from lean and obese Zucker rats


The metabolic differences in vitro between genetic and dietary obese rats in the uptake of ammonium and amino acids by the liver and their use for ureogenesis have been assayed using hepatocytes isolated from Lean, Obese Zucker (Genetic obese) rats and Dietary obese rats. The hepatocytes of genetic obese animals took up more ammonium and produced higher… (More)
DOI: 10.1023/A:1007003519678


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