Ammonia-related changes in cerebral electrogenesis in healthy subjects and patients with cirrhosis

@article{Bersagliere2013AmmoniarelatedCI,
  title={Ammonia-related changes in cerebral electrogenesis in healthy subjects and patients with cirrhosis},
  author={Alessia Bersagliere and Iolanda D Raduazzo and Sami Schiff and Angelo Gatta and Sara Montagnese},
  journal={Clinical Neurophysiology},
  year={2013},
  volume={124},
  pages={492-496}
}
OBJECTIVE To study the effect of hyperammonaemia on the wake electroencephalogram (EEG) of patients with cirrhosis and healthy volunteers. METHODS Wake EEGs were recorded prior to and after the induction of controlled hyperammonaemia in 10 patients with cirrhosis and 10 matched healthy volunteers. RESULTS At baseline, patients had higher ammonaemia than healthy volunteers and their dominant EEG rhythm was slower and of higher amplitude. Induced hyperammonaemia resulted in increased spectral… CONTINUE READING

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