Amlodipine besylate-excipients interaction in solid dosage form.

  title={Amlodipine besylate-excipients interaction in solid dosage form.},
  author={A. A. Abdoh and Mariam M Al-Omari and Adnan A. Badwan and Abdul Muttaleb Yousef Jaber},
  journal={Pharmaceutical development and technology},
  volume={9 1},
This article studies the compatibility of amlodipine besylate in its solid formulations with various drug excipients. The various factors affecting amlodipine besylate stability were studied using high-performance liquid chromatography (HPLC). It has been found that binary 1:1 mixtures of amlodipine besylate and an excipient are stable at 65 degrees C and 40 degrees C/75% RH. Further investigations were conducted to study the stability of amlodipine besylate in multicomponent mixtures… CONTINUE READING


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