Amiodarone for long-term management of patients with hypertrophic cardiomyopathy.

  title={Amiodarone for long-term management of patients with hypertrophic cardiomyopathy.},
  author={William J. McKenna and Louise Harris and Edward Rowland and A Kleinebenne and Dennis M. Krikler and Celia M. Oakley and John Forrest Goodwin},
  journal={The American journal of cardiology},
  volume={54 7},
Fifty-three patients with hypertrophic cardiomyopathy who had serious arrhythmias (45 patients), refractory chest pain (5 patients) or a high risk of sudden death (3 patients) received amiodarone for 6 to 96 months (median 18) after completion of a loading and an initial maintenance period. The dose of amiodarone was altered by 50 to 200 mg/day at 3- to 6-month intervals, guided by electrocardiographic monitoring, plasma drug level measurements and side-effect questionnaires. Ventricular… CONTINUE READING


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