Aminophylline

@article{1991Aminophylline,
  title={Aminophylline},
  author={藥劑部},
  journal={Reactions Weekly},
  year={1991},
  volume={371},
  pages={4}
}
  • 藥劑部
  • Published 1991
  • Medicine
  • Reactions Weekly
A methylxanthine and derivative of theophylline. Aminophylline relaxes smooth muscles, particularly bronchial muscles. T his xanthine most likely exerts its effect by inhibiting cAMP or cGMP phosphodiesterases, thereby increasing levels of the second messenger cAMP or cGMP intracellularly. Other mode of actions include an adenosine antagonistic effect on the activity of CD4 lymphocytes and mediator release from mast cells thereby decreasing lung sensitivity to allergens and other substances… Expand
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