Aminopeptidase N is involved in cell motility and angiogenesis: its clinical significance in human colon cancer.

@article{Hashida2002AminopeptidaseNI,
  title={Aminopeptidase N is involved in cell motility and angiogenesis: its clinical significance in human colon cancer.},
  author={Hiroki Hashida and Arimichi Takabayashi and Michiyuki Kanai and Masashi Adachi and Keiichi Kondo and Nobuoki Kohno and Yoshio Yamaoka and Masayuki Miyake},
  journal={Gastroenterology},
  year={2002},
  volume={122 2},
  pages={376-86}
}
BACKGROUND & AIMS The molecular basis of cell motility is highly complex and is controlled by a number of molecular systems, whereas angiogenesis is an important biological component of tumor progression. The aims of this study were to investigate the possible involvement of proteins at the cell surface in controlling cell motility and angiogenesis, and to identify the cell surface molecules involved in gastrointestinal tumors. METHODS We addressed these issues using functional monoclonal… CONTINUE READING

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