Aminopeptidase N is a major receptor for the enteropathogenic coronavirus TGEV

Abstract

CORONAVIRUSES, like many animal viruses, are characterized by a restricted host range and tissue tropism1. Transmissible gastroenteritis virus (TGEV), a major pathogen causing a fatal diarrhoea in newborn pig, replicates selectively in the differentiated enterocytes covering the villi of the small intestine2. To investigate the molecular determinants of the… (More)
DOI: 10.1038/357417a0

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