Aminopeptidase N (CD13) is a molecular target of the cholesterol absorption inhibitor ezetimibe in the enterocyte brush border membrane.

@article{Kramer2005AminopeptidaseN,
  title={Aminopeptidase N (CD13) is a molecular target of the cholesterol absorption inhibitor ezetimibe in the enterocyte brush border membrane.},
  author={Werner Kramer and Frank Girbig and Daniel Corsiero and Anja Pfenninger and Wendelin Frick and Gerhard J{\"a}hne and Matthias Rhein and Wolfgang Wendler and Friedrich Lottspeich and Elisabeth O. Hochleitner and Evelyn Orso and Gerd Schmitz},
  journal={The Journal of biological chemistry},
  year={2005},
  volume={280 2},
  pages={1306-20}
}
Intestinal cholesterol absorption is an important regulator of serum cholesterol levels. Ezetimibe is a specific inhibitor of intestinal cholesterol absorption recently introduced into medical practice; its mechanism of action, however, is still unknown. Ezetimibe neither influences the release of cholesterol from mixed micelles in the gut lumen nor the… CONTINUE READING