Aminopeptidase M and dipeptidyl peptidase IV activity in epithelial skin tumors: a histochemical study.

@article{Moehrle1995AminopeptidaseMA,
  title={Aminopeptidase M and dipeptidyl peptidase IV activity in epithelial skin tumors: a histochemical study.},
  author={Matthias Moehrle and Bettina Schlagenhauff and Christian Klessen and Gernot Rassner},
  journal={Journal of cutaneous pathology},
  year={1995},
  volume={22 3},
  pages={
          241-7
        }
}
The activities of microsomal alanylaminopeptidase (APM EC 3.4.11.2) and of dipeptidyl dipeptidase IV (DPP IV EC 3.4.14.5) were histochemically studied in frozen sections of normal skin, seborrheic keratosis, basal cell carcinoma, solar keratosis, Bowen's disease and squamous cell carcinoma using amino acid- or peptide-4-methoxy-2-naphthylamides as specific chromogenic substrates. Compared to biochemical and immunohistochemical methods, the histochemical technique used in this study allows… CONTINUE READING
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