Aminolysis of aryl ester using tertiary amine as amino donor via C-O and C-N bond activations.


An aminolysis reaction between various aryl esters and inert tertiary amines by C-O and C-N bond activations has been developed for the selective synthesis of a broad scope of tertiary amides under neutral and mild conditions. The mechanism may undergo the two key steps of oxidative addition of acyl C-O bond in parent ester and C-N bond cleavage of tertiary… (More)
DOI: 10.1021/jo4023974


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