Aminolysis of 4-nitrophenyl phenyl carbonate and thionocarbonate: effects of amine nature and modification of electrophilic center from C[double bond]O to C[double bond]S on reactivity and mechanism.

@article{Um2008AminolysisO4,
  title={Aminolysis of 4-nitrophenyl phenyl carbonate and thionocarbonate: effects of amine nature and modification of electrophilic center from C[double bond]O to C[double bond]S on reactivity and mechanism.},
  author={I. Um and Sora Yoon and Hye-Ran Park and Hyun-Joo Han},
  journal={Organic & biomolecular chemistry},
  year={2008},
  volume={6 9},
  pages={
          1618-24
        }
}
  • I. Um, Sora Yoon, +1 author Hyun-Joo Han
  • Published 2008
  • Chemistry, Medicine
  • Organic & biomolecular chemistry
  • A kinetic study is reported for the reactions of 4-nitrophenyl phenyl carbonate (5) and thionocarbonate (6) with a series of alicyclic secondary amines in 80 mol% H(2)O-20 mol% DMSO at 25.0 +/- 0.1 degrees C. The plots of k(obsd) vs. amine concentration are linear for the reactions of 5. On the contrary, the plots for the corresponding reactions of 6 curve upward as a function of increasing amine concentration, indicating that the reactions proceed through two intermediates (i.e., a… CONTINUE READING
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