Aminoguanidine reduces regional albumin clearance but not urinary albumin excretion in streptozotocin-diabetic rats

@article{Huijberts1994AminoguanidineRR,
  title={Aminoguanidine reduces regional albumin clearance but not urinary albumin excretion in streptozotocin-diabetic rats},
  author={Dr. M. S. P. Huijberts and Bruce H. R. Wolffenbuttel and Francy R L Crijns and Arie C. Nieuwenhuijzen Kruseman and Marc H. A. Bemelmans and Harry A. J. Struijker Boudier},
  journal={Diabetologia},
  year={1994},
  volume={37},
  pages={10-14}
}
Advanced glycation end-product-formation is thought to play a role in the development of diabetic angiopathy. By altering the structure of different extracellular matrix components advanced glycation end-products might affect vascular and glomerular permeability. In this study we investigated the effect of treatment with an inhibitor of advanced glycation… CONTINUE READING