Aminoguanidine inhibits the AGE-RAGE axis to modulate the induction of periodontitis but has limited effects on the progression and recovery of experimental periodontitis: a preliminary study.

Abstract

BACKGROUND Advanced glycation end products (AGE) have been found in inflamed gingival tissue and have been shown to interfere with the integrity of extracellular matrix and cell-matrix interactions. This study aims to investigate the modulatory effect of aminoguanidine (AG), an AGE inhibitor, in various stages of experimental periodontitis. METHODS Thirty… (More)
DOI: 10.1902/jop.2013.130238

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Cite this paper

@article{Chang2014AminoguanidineIT, title={Aminoguanidine inhibits the AGE-RAGE axis to modulate the induction of periodontitis but has limited effects on the progression and recovery of experimental periodontitis: a preliminary study.}, author={Po-Chun Chang and Li Yen Chong and Sheng-Chueh Tsai and Lum Peng Lim}, journal={Journal of periodontology}, year={2014}, volume={85 5}, pages={729-39} }