Aminoglycoside treatment and renal prostaglandin excretion in premature infants.

@article{Khl1985AminoglycosideTA,
  title={Aminoglycoside treatment and renal prostaglandin excretion in premature infants.},
  author={Peter Gonne K{\"u}hl and K Soeding and Hannsj{\"o}rg W. Seyberth},
  journal={Developmental pharmacology and therapeutics},
  year={1985},
  volume={8 1},
  pages={61-7}
}
During prospective studies of indomethacin treatment of symptomatic patent ductus arteriosus, the question arose whether aminoglycosides alter renal prostaglandin metabolism. Adopting the matched-pair method, we retrospectively analyzed creatinine clearances, urine output and renal PGE2 and PGF2 alpha excretion in preterm infants with and without… CONTINUE READING