Aminoglycoside resistance in enterococci.

  title={Aminoglycoside resistance in enterococci.},
  author={Joseph Chow},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  volume={31 2},
  • Joseph Chow
  • Published 2000 in
    Clinical infectious diseases : an official…
High-level aminoglycoside resistance in enterococci is mediated generally by aminoglycoside-modifying enzymes, which eliminate the synergistic bactericidal effect usually seen when a cell wall-active agent is combined with an aminoglycoside. Clinical microbiology laboratories currently screen for aminoglycoside resistance in enterococci by testing gentamicin and streptomycin susceptibility. If the recently detected aminoglycoside resistance genes, aph(2")-Ib, aph(2")-Ic, and aph(2")-Id, become… CONTINUE READING