Aminoacyl-tRNA synthetase complexes: beyond translation

@article{Lee2004AminoacyltRNASC,
  title={Aminoacyl-tRNA synthetase complexes: beyond translation},
  author={Sang Won Lee and Byeong Hoon Cho and Sang Gyu Park and Sunghoon Kim},
  journal={Journal of Cell Science},
  year={2004},
  volume={117},
  pages={3725 - 3734}
}
Although aminoacyl-tRNA synthetases (ARSs) are housekeeping enzymes essential for protein synthesis, they can play non-catalytic roles in diverse biological processes. Some ARSs are capable of forming complexes with each other and additional proteins. This characteristic is most pronounced in mammals, which produce a macromolecular complex comprising nine different ARSs and three additional factors: p43, p38 and p18. We have been aware of the existence of this complex for a long time, but its… 

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