Aminoacyl-tRNA synthesis.

  title={Aminoacyl-tRNA synthesis.},
  author={Michael Ibba and D. Soll},
  journal={Annual review of biochemistry},
Aminoacyl-tRNAs are substrates for translation and are pivotal in determining how the genetic code is interpreted as amino acids. The function of aminoacyl-tRNA synthesis is to precisely match amino acids with tRNAs containing the corresponding anticodon. This is primarily achieved by the direct attachment of an amino acid to the corresponding tRNA by an aminoacyl-tRNA synthetase, although intrinsic proofreading and extrinsic editing are also essential in several cases. Recent studies of… CONTINUE READING
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