Amino-terminal sequence of a carcinoembryonic antigen-like glycoprotein isolated from the colonic lavages of healthy individuals.

@article{Shively1978AminoterminalSO,
  title={Amino-terminal sequence of a carcinoembryonic antigen-like glycoprotein isolated from the colonic lavages of healthy individuals.},
  author={John E Shively and Charles W. Todd and Vay Liang W. Go and Marianne L Egan},
  journal={Cancer research},
  year={1978},
  volume={38 3},
  pages={503-5}
}
A glycoprotein has been isolated from the colonic lavages of healthy individuals that is immunologically equivalent to carcinoembryonic antigen purified from tumor tissue. The NH2-terminal sequence of the glycoprotein from normal colon lavages is Lys-Leu-Thr-lle-Glu-Ser-Thr-Pro-Phe-(Asn)-Val-Ala-Glu-Gly-Lys-Glu-Val-(Leu,lle)-(Leu,lle)-(Leu,lle)-Val-(His,Arg?)-?-(Leu,lle). This is homologous to the NH2-terminal sequence of 23 of the first 24 amino acids of carcinoembryonic antigen isolated from… CONTINUE READING

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Isolation and Characterization of Carci noembryonic Antigen (CEA) Extracted From Normal Human Colon Mucosa

  • R. Pritsche, J. P. Mach
  • Immunochemistry,
  • 1977
2 Excerpts

Carcinoembryonic Antigen

  • M. Egan
  • 1974
1 Excerpt

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