Amino-terminal fragment of the prohormone brain-type natriuretic peptide in rheumatoid arthritis.

@article{Solus2008AminoterminalFO,
  title={Amino-terminal fragment of the prohormone brain-type natriuretic peptide in rheumatoid arthritis.},
  author={Joseph F. Solus and Cecilia P Chung and Annette M. Oeser and Ingrid Avalos and Tebeb Gebretsadik and Ayumi Shintani and Paolo M Raggi and Tuulikki Sokka and Theodore Pincus and Charles M. Stein},
  journal={Arthritis and rheumatism},
  year={2008},
  volume={58 9},
  pages={2662-9}
}
OBJECTIVE Increased concentrations of N-terminal pro-brain natriuretic peptide (NT-proBNP) are associated with cardiovascular morbidity and mortality, but little is known about their relationship to chronic inflammation. Patients with rheumatoid arthritis (RA) have chronic inflammation, increased arterial stiffness, and accelerated coronary atherosclerosis. This study was undertaken to test the hypothesis that NT-proBNP concentrations are elevated in patients with RA and are associated with… CONTINUE READING