Amino acid substitutions at positions 242, 255 and 268 in rabies virus glycoprotein affect spread of viral infection.

@article{Ito2010AminoAS,
  title={Amino acid substitutions at positions 242, 255 and 268 in rabies virus glycoprotein affect spread of viral infection.},
  author={Yuki Ito and Naoto Ito and Shouichiro Saito and Tatsunori Masatani and Keisuke Nakagawa and Yasuro Atoji and Makoto Sugiyama},
  journal={Microbiology and immunology},
  year={2010},
  volume={54 2},
  pages={89-97}
}
Rabies virus Nishigahara strain kills adult mice after intracerebral inoculation, whereas the derivative RC-HL strain does not. It has previously been reported by us that the R(G 242/255/268) strain, in which amino acids at positions 242, 255 and 268 on the G protein have been replaced by those from the Nishigahara strain in the genetic background of the RC… CONTINUE READING